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N-nitrosodimethylamine (NDMA) in Ranitidine

In the UK this week there was a recall of the stomach acid reducing medicine Zantac by the MHRA due to unacceptably high levels of the impurity n-nitrosodimethylamine (NDMA). The active ingredient in Zantac, Ranitidine was found to be contaminated with the highly toxic and potentially carcinogenic impurity.
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    N-nitrosodimethylamine (NDMA) in Ranitidine

    In the UK this week there was a recall of the stomach acid reducing medicine Zantac by the MHRA due to unacceptably high levels of the impurity n-nitrosodimethylamine (NDMA). The active ingredient in Zantac, Ranitidine was found to be contaminated with the highly toxic and potentially carcinogenic impurity....
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    Blog,

    Brexit and the chemical industry

    Technical Director Iain Nicolson participated in a round table to discuss brexit and the chemical industry. The meeting with government ministers and leaders from the chemical industry will shape some of the key points relating to strategy for Brexit negotiations and post-Brexit plans.
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    Fipronil in eggs

    Another recent food scandal is in the headlines this Summer with the revelation that eggs from Belgium had been contaminated with the toxic insecticide Fipronil. Fipronil, an insecticide used to protect both livestock and crops from lice, ticks, mites and fleas.
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    Pharma Outsourcing

    Custom synthesis outsourcing in the pharmaceutical and life science industry in early stage pharmaceutical development offers several advantages. By entrusting outsource partners to handle customs synthesis of API’s, intermediates or several steps in a synthetic route, a pharma company or CRO can reduce the u...
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    Tianjin Explosion

    This week, two major events occurred in China which may have opposite effects on the chemical sourcing and export business. Firstly the devaluation of the Renminbi by the Chinese government on three consecutive days during the week.
  • Blog,

    Tianjin Explosion

    This week, two major events occurred in China which may have opposite effects on the chemical sourcing and export business. Firstly the devaluation of the Renminbi by the Chinese government on three consecutive days during the week.
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    Custom Synthesis Article

    Oliver Smith co-authors custom synthesis article for China Chemical Review (http://www.ccr.com.cn/new/) for pharma and agro companies.
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    Innovation in the pharmaceutical industry

    China has long been one of the key pharmaceutical manufacturing hubs in the world, providing the world with intermediates, pharmaceutical ingredients and generic drugs.
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    Chemical Shipping Regulations in China

    Companies from across the chemical industry who have sourced products from China before will have a story to tell about receiving a chemical under an incorrect/fake name, but why are companies still doing it?
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    Agrochemical development in China

    The recent EU ban on the use of neonicotinoids will create a treatment vacuum that alternative products will be required to fill. Agrochemical development is essential to increase efficacy and reduce environmental impact.
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    EU pesticide ban

    This week the European Commission voted to ban the use of neonicotinoid insecticides in the EU in response to fears about dwindling bee numbers. It has been claimed with the support of scientific studies that this class of insecticide is if not wholly then partially responsible for the decline in the numbers ...
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    Horsemeat Scandal

    There is a saying in Chinese preaching the virtues of eating Donkey. 天上龙肉, 地上驴肉(Tiānshàng lóng ròu, dìshàng lǘ ròu) means in heaven you can eat dragon meat but while on earth the next best thing is donkey meat.