FB Pharmtech | Custom Synthesis

Custom Synthesis

FB Pharmtech provides custom synthesis services to customers across the chemical industry, including drug development companies, contract research/manufacturing organisations, chemical catalogue companies, government-related bodies, academic institutions and life science start-up companies.

Our custom synthesis service is reliable, cost-effective, and based on technical innovation and clear, open communication. We are committed to ensuring that our customers receive the best possible service at the best price.

landscape image

FB Pharmtech specialises in the custom synthesis of organic small molecules including impurities, metabolites, intermediates; and molecules for drug discovery and development. FB Pharmtech's chemists have successfully completed hundreds of custom synthesis projects on scales ranging from mg - multi kg.

landscape image

FB Pharmtech has a dedicated team of Shanghai based chemists undertaking custom synthesis projects on scales from mg-multi kg.

We have strengths in the custom synthesis of molecules for drug development, impurity reference standards and metabolites on the mg-100g scale, having successfully completed many challenging synthesis projects for these types of molecules for applications in both pharmaceutical and plant protection

  • Dedicated team of chemists for synthesis and process development
  • Successful track-record in performing challenging, multi-step syntheses
  • Fixed cost synthesis
  • FTE service
  • Small molecule drug development, medicinal chemistry and process development service
  • 32 Fume hoods, 3 kilo labs, one pressure lab
  • Preparative HPLC for separation work, including chiral prep-HPLC

We also have the capabilities and facilities to support process development and scale-up, supporting the manufacture of intermediates and fine chemicals at kg-Mt scale, features include

  • Professional facilities for pilot production
  • 500 litre reactors and 2 x 1000 litres, 2 x 2000L, 2 x 3000L, 2 x 5000L
  • Pressure Lab with 300 L autoclave up to 200 atm
  • Fractional distillation and re-crystallization facilities
  • An experienced team for scale-up
  • Well-equipped with steam, cooling, vacuum systems
  • Waste water treatment and dangerous goods warehouse

We know that our customers understand custom synthesis can be challenging and painstaking work that requires extensive development and optimisation.

That's why FB Pharmtech is committed to providing the best possible service to our customers, we provide regular technical updates on the progress of a synthesis project and communicate the challenges, targets and timescales to support our customer's research, planning & development

We utilise a number of analytical techniques in support of our custom synthesis work including 400MHz NMR, HPLC, MS, GC, prep-HPLC, Karl Fischer water content, elemental analysis, optical rotation, particle size analysis and a physical chemical tests; which are all carried out in-house

related products

Latest from FB Pharmtech

  • News,

    FB Pharmtech New Website & Branding

    FB Pharmtech has been providing custom synthesis and sourcing services since 2012, and to mark the achievement of being in business for 10 years, we have introduced a new set of branding and a new website.
  • News,


    N-nitrosodimethylamine (NDMA) in Ranitidine

    In the UK this week there was a recall of the stomach acid reducing medicine Zantac by the MHRA due to unacceptably high levels of the impurity n-nitrosodimethylamine (NDMA). The active ingredient in Zantac, Ranitidine was found to be contaminated with the highly toxic and potentially carcinogenic impurity....
  • News,


    Brexit and the chemical industry

    Technical Director Iain Nicolson participated in a round table to discuss brexit and the chemical industry. The meeting with government ministers and leaders from the chemical industry will shape some of the key points relating to strategy for Brexit negotiations and post-Brexit plans.
  • Blog,

    Fipronil in eggs

    Another recent food scandal is in the headlines this Summer with the revelation that eggs from Belgium had been contaminated with the toxic insecticide Fipronil. Fipronil, an insecticide used to protect both livestock and crops from lice, ticks, mites and fleas.
  • Case Study,

    Market Research Case Study

    A chemical company sourcing from China had seen unexpected increases in the prices of a chemical they were purchasing. The customer wanted to understand the reasons for the price increase in order to make strategic decisions about their future sourcing.
  • Blog,

    Pharma Outsourcing

    Custom synthesis outsourcing in the pharmaceutical and life science industry in early stage pharmaceutical development offers several advantages. By entrusting outsource partners to handle customs synthesis of API’s, intermediates or several steps in a synthetic route, a pharma company or CRO can reduce the u...